祝贺张晓雨的文章在Molecules接受发表！

张晓雨在Molecules发表题为《Advance Progress in Assembly Mechanisms of Carrier-Free Nanodrugs for Cancer Treatment》的文章。这篇综述总结了基于不同类型的组装机制和策略的无载体纳米药物的最新进展和应用，其中包括非共价相互作用、共价键和非共价相互作用的组合以及金属离子配位自组装。根据它们的组装和抗肿瘤应用详细介绍了这些无载体纳米药物。最后，讨论了无载体纳米药物在未来开发和临床应用中的前景和存在的挑战。这次全面综述希望为合理设计更有效的无载体纳米药物系统和推进临床癌症和其他疾病（例如细菌感染）感染治疗提供新的见解。

摘要：Nanocarriers have been widely studied and applied in the field of cancer treatment. However, conventional nanocarriers still suffer from complicated preparation processes, low drug loading, and potential toxicity of carriers themselves. To tackle the hindrance, carrier-free nanodrugs with biological activity have received increasing attention in cancer therapy. Extensive efforts have been made to exploit new self-assembly methods and mechanisms to expand the scope of carrier-free nanodrugs with enhanced therapeutic performance. In this review, we summarize the advanced progress and applications of carrier-free nanodrugs based on different types of assembly mechanisms and strategies, which involved noncovalent interactions, a combination of covalent bonds and noncovalent interactions, and metal ions-coordinated self-assembly. These carrier-free nanodrugs are introduced in detail according to their assembly and antitumor applications. Finally, the prospects and existing challenges of carrier-free nanodrugs in future development and clinical application are discussed. We hope that this comprehensive review will provide new insights into the rational design of more effective carrier-free nanodrug systems and advancing clinical cancer and other diseases (e.g., bacterial infections) infection treatment.