谢文升 副教授

办公地址：北京化工大学朝阳校区科技大厦301-3

联系邮箱：xws@buct.edu.cn

教育背景：

2020/09-2023/06，清华大学，化学系，博士，导师：危岩 （化学生物学）
2016/09-2018/06，清华大学，马克思主义学院，硕士，导师：朱安东 （政治经济学）

2017/03-2017/10，University of New South Wales （UNSW），短期交流，导师：Sophia Gu（肿瘤诊断）
2015/09-2018/06，清华大学，材料学院，硕士，导师：赵凌云 （生物材料）

2013/09-2015/06，清华大学，计算机系，学士 （计算机辅修）
2011/09-2015/06，清华大学，材料学院，学士 （材料科学与工程）

工作经历：

2023/07-至今，北京化工大学，生命科学与技术学院，副教授

2019/02-2020/08，碧桂园集团广东博智林机器人有限公司，高级经理

2018/07-2019/01，碧桂园控股集团，超级碧业生

主要研究领域：

已期刊发表SCI论文50余篇，其中高被引论文1篇，热点论文3篇，被引2300余次，H-index为23，申请授权发明专利5项，主要研究领域如下：

（1）肿瘤联合治疗用可编程纳米生物材料的开发；

J. Mater. Chem. B, 2024, 12, 1194-1207; Prog. in Mater. Sci.2023, 138, 101145; Adv Funct Mater 2022, 32 (12), 2107518； ACS Appl. Mater. Interfaces 2022, 14 (4), 4995–5008； Nanoscale 2021, 13 (34), 14525–14537； Adv. Healthcare Mater. 2019, 8 (14), 1900203； J. Biomedical Nanotech. 2018, 14, 362–370.

（2）药物递送系统用可降解纳米生物材料的开发；

ACS Nano 2024, 18(9), 6975–6989; Chem. Eng. J. 2022, 446, 137310； Adv. Sci. 2022, 9 (4), 2104101； Chem. Eng. J. 2022, 438, 135372； Chem. Eng. J. 2023, 451, 138617； ACS Appl. Bio Mater. 2020, 3 (9), 5845–5855.

（3）基于工程化双歧杆菌的“生物混合细菌机器人”研发；

ACS nano 2024, 18(11), 8017–8028; ACS Appl. Mater. Interfaces, 2024, 16(3), 3202-3214; 

代表性著作：
2024                                 
（1） Guo, Z.; Gao, X.; Lu, J.; Li, Y.; Jin, Z.; Fahad, A.; Pambe, N. U.; Ejima, H.; Sun, X.; Wang, X.; Xie, W.*; Zhang, G.*; Zhao, L.* Apoptosis and Paraptosis Induced by Disulfiram-Loaded Ca2+/Cu2+ Dual-Ions Nano Trap for Breast Cancer Treatment. ACS Nano 2024, 18 (9), 6975–6989. https://doi.org/10.1021/acsnano.3c10173.
（2） Feng, W#; Chittò, M.#; Xie, W.#; Ren, Q.; Liu, F.; Kang, X.; Zhao, D.; Li, G.; Moriarty, T. F.; Wang, X. Poly(d-Amino Acid) Nanoparticles Target Staphylococcal Growth and Biofilm Disassembly by Interfering with Peptidoglycan Synthesis. ACS Nano 2024, 18 (11), 8017–8028. https://doi.org/10.1021/acsnano.3c10983.
（3） Kang, X.; Yang, X.; Bu, F.; Feng, W.; Liu, F.; Xie, W.; Li, G.; Wang, X. GSH/pH Cascade-Responsive Nanoparticles Eliminate Methicillin-Resistant Staphylococcus Aureus Biofilm via Synergistic Photo-Chemo Therapy. ACS Appl. Mater. Interfaces 2024, 16 (3), 3202–3214. https://doi.org/10.1021/acsami.3c17198.
（4） Liu, Z.; Ma, Y.; Ye, J.; Li, G.; Kang, X.; Xie, W.*; Wang, X.* Drug Delivery System for Enhanced Tumour Treatment by Eliminating Intra-Tumoral Bacteria. J. Mater. Chem. B 2024, 12, 1194–1207. https://doi.org/10.1039/d3tb02362a.

2023                                     
（5） Xie, W.; Guo, Z.; Zhao, L.; Wei, Y. The Copper Age in Cancer Treatment: From Copper Metabolism to Cuproptosis. Prog. Mater. Sci. 2023, 138, 101145. https://doi.org/10.1016/j.pmatsci.2023.101145.
（6） Huang, H.; Xie, W.; Hu, D.; He, X.; Li, R.; Zhang, X.; Wei, Y. Type I Photodynamic Therapy with a Self-Degradable Conjugated Polyelectrolyte in Combination with CpG Adjuvant for Cancer Immunotherapy. Chem Eng J 2023, 451, 138617. https://doi.org/10.1016/j.cej.2022.138617.
（7） Guo, Z.#; Xie, W.#; Gao, X.; Lu, J.; Ye, J.; Li, Y.; Fahad, A.; Zhang, G.; Zhao, L. Nanoheterostructure by Liquid Metal Sandwich-Based Interfacial Galvanic Replacement for Cancer Targeted Theranostics. Small 2023, 19 (22), 2300751. https://doi.org/10.1002/smll.202300751.
（8） Guo, Z.; Gao, X.; Lu, J.; Xu, W.; Ye, J.; Li, Y.; Xie, W.*; Zhao, L.* Recent Advances for Liquid Metals: Synthesis, Modification and Bio-Applications. J Mater Sci Technol 2023, 143, 153–168. https://doi.org/10.1016/j.jmst.2022.08.053.

2022                                         
（9） Xie, W.; Zhang, G.; Guo, Z.; Huang, H.; Ye, J.; Gao, X.; Yue, K.; Wei, Y.; Zhao, L. Shape-Controllable and Kinetically Miscible Copper–Palladium Bimetallic Nanozymes with Enhanced Fenton-like Performance for Biocatalysis. Materials Today Bio 2022, 16, 100411. https://doi.org/10.1016/j.mtbio.2022.100411.
（10） Huang, H.; Xie, W.; Wan, Q.; Mao, L.; Hu, D.; Sun, H.; Zhang, X.; Wei, Y. A Self‐degradable Conjugated Polymer for Photodynamic Therapy with Reliable Postoperative Safety. Adv Sci 2022, 9 (4), 2104101. https://doi.org/10.1002/advs.202104101.
（11） Xie, W.; Ye, J.; Guo, Z.; Lu, J.; Xu, W.; Gao, X.; Huang, H.; Hu, R.; Mao, L.; Wei, Y.; Zhao, L. TME-Responded Full-Biodegradable Nanocatalyst for Mitochondrial Calcium Overload-Induced Hydroxyl Radical Bursting Cancer Treatment. Chem. Eng. J. 2022, 438, 135372. https://doi.org/10.1016/j.cej.2022.135372.
（12） Guo, Z.#; Xie, W.#; Zhang, Q.; Lu, J.; Ye, J.; Gao, X.; Xu, W.; Fahad, A.; Xie, Y.; Wei, Y.; Wu, H.; Boyer, C.; Zhao, L.; Gu, Z. Photoactivation-Triggered in Situ Self-Supplied H2O2 for Boosting Chemodynamic Therapy via Layered Double Hydroxide-Mediated Catalytic Cascade Reaction. Chem. Eng. J. 2022, 446, 137310. https://doi.org/10.1016/j.cej.2022.137310.
（13） Xie, W.; Ye, J.; Guo, Z.; Lu, J.; Gao, X.; Wei, Y.; Zhao, L. Ultrafast Fabrication of Iron/Manganese Co-Doped Bismuth Trimetallic Nanoparticles: A Thermally Aided Chemodynamic/Radio-Nanoplatform for Low-Dose Radioresistance. ACS Appl Mater Interfaces 2022, 14 (19), 21931–21944. https://doi.org/10.1021/acsami.2c02484.
（14） Xie, W.; Lu, J.; Guo, Z.; Guo, X.; Chi, Y.; Ye, J.; Zhang, J.; Xu, W.; Zhao, L.; Wei, Y. Necroptosis-Elicited Host Immunity: GOx-Loaded MoS2 Nanocatalysts for Self-Amplified Chemodynamic Immunotherapy. Nano Res 2022, 15 (3), 2244–2253. https://doi.org/10.1007/s12274-021-3763-7.

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教师寄语:

天行健·君子以自强不息，不要忘记当初带着梦想出发时的自己！

招生要求：

对科研：岁月漫长心怀热爱；对未来：星辰大海携手共赴